Corrigendum: Clinical Efficacy of Oral Ganciclovir for Prophylaxis and Treatment of Recurrent Herpes Simplex Keratitis
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1. Mamelak AN, Obana WG, Flaherty JF, Rosenblum ML. Nocardial brain abscess: Treatment strategies and factors influencing outcome. Neurosurgery 1994;35:622‐31. doi: 10.1227/00006123‐199410000‐00007. 2. Gendelman H, Rappaport J, Hickey W. The blood‐brain barrier: Defensive shield or a perpetrator of microbial invasion? J Neurovirol 1999;5:533‐7. doi: 10.3109/13550289909021283. 3. Wallace RJ Jr, Steele LC, Sumter G, Smith JM. Antimicrobial susceptibility patterns of Nocardia asteroides. Antimicrob Agents Chemother 1988;32:1776‐9. doi: 10.1128/AAC.32.12.1776. 4. Taj‐Aldeen SJ, Deshmukh A, Doiphode S, Wahab AA, Allangawi M, Almuzrkchi A, et al. Molecular identification and susceptibility pattern of clinical Nocardia species: Emergence of Nocardia crassostreae as an agent of invasive nocardiosis. Can J Infect Dis Med Microbiol 2013;24:e33‐8. and in this respect did not fit any of the patterns identified by Wallace et al. for Nocardia asteroides which caused the majority of human Nocardia infections.[3] It also differs from the only other case reported in humans while this manuscript was in preparation.[4] In Figure 1: Axial T1‐weighted postcontrast magnetic resonance imaging scan ring enhancing lesion at presentation (a) and 4 weeks after treatment (b). b a
منابع مشابه
Ganciclovir ophthalmic gel 0.15% for the treatment of acute herpetic keratitis: background, effectiveness, tolerability, safety, and future applications
Eye disease due to herpes simplex virus (HSV) is a leading cause of ocular morbidity and the number one infectious cause of unilateral corneal blindness in the developed parts of the globe. Recurrent keratitis can result in progressive corneal scarring, thinning, and vascularization. Antiviral agents employed against HSV have primarily been nucleoside analogs. Early generation drugs included id...
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Herpes simplex keratitis (HSK) is a major cause of corneal blindness in the world. Following the primary infection, the virus enters into a latent phase. Recurrent infectious or immune keratitis cause structural damage to the cornea, scarring, and may lead to blindness. Several commercially available topical and oral antiviral drugs for HSK are currently available. However, toxicity and low pat...
متن کاملTopical ganciclovir in the treatment of acute herpetic keratitis
Herpetic keratitis is caused by herpes simplex virus (HSV) and is a common cause of corneal blindness. Following a primary ocular herpetic infection, latency of the virus occurs, followed by subsequent recurrences of herpetic keratitis. Such recurrences may lead to structural damage of the cornea. Recurrent herpetic keratitis is a common indication for corneal transplantation. Recurrences of he...
متن کاملClinical Efficacy of Oral Ganciclovir for Prophylaxis and Treatment of Recurrent Herpes Simplex Keratitis
BACKGROUND Herpes simplex keratitis (HSK) caused by herpes simplex virus 1 (HSV-1), which has high recurrent rate and incidence of severe vision loss, is the leading cause of infectious blindness in the world. The aim was to explore the clinical efficacy of oral ganciclovir (GCV) in the prevention of recurrent HSK. METHODS A multicenter, prospective, randomized, single-blind, and controlled c...
متن کاملRandomised trial of ganciclovir and acyclovir in the treatment of herpes simplex dendritic keratitis: a multicentre study.
AIMS This study was designed to assess the relative efficacy of topical ganciclovir 0.15% gel and acyclovir 3% ointment in the treatment of herpes simplex dendritic keratitis. METHODS Both treatment modalities were administered on a five times daily basis to patients suffering from herpes simplex keratitis. Patients were assigned randomly to one of the two treatment groups for the purpose of ...
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